Masi, Mirco; Poppi, Laura; Previtali, Viola; Nelson, Shannon R; Wynne, Kieran; Varignani, Giulia; Falchi, Federico; Veronesi, Marina; Albanesi, Ennio; Tedesco, Daniele; De Franco, Francesca; Ciamarone, Andrea; Myers, Samuel H; Ortega, Jose Antonio; Bagnolini, Greta; Ferrandi, Giovanni; Farabegoli, Fulvia; Tirelli, Nicola; Di Stefano, Giuseppina; Oliviero, Giorgio; Walsh, Naomi; Roberti, Marinella; Girotto, Stefania; Cavalli, Andrea, Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity, «CELL DEATH DISCOVERY», 2025, 11, pp. 1 - 23 [Scientific article]
Romeo, E.; Saccoliti, F.; Ocello, R.; Andonaia, A.; Allegretta, C.; Pastorino, C.; Pedemonte, N.; Falchi, F.; Laselva, O.; Bandiera, T.; Bertozzi, F., Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Potent CFTR Corrector, «JOURNAL OF MEDICINAL CHEMISTRY», 2025, 68, pp. 4596 - 4618 [Scientific article]
Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Falchi, Federico; Previtali, Viola; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors
to trigger synthetic lethality with Olaparib in pancreatic cancer cells, in: National Congress of the Italian Chemistry Society 2024, 2024(atti di: SCI 2024 Chemistry ELEMENTS OF FUTURE, Milano, 26th August 2024) [Poster]
Bernetti, Mattia; Bosio, Stefano; Bresciani, Veronica; Falchi, Federico; Masetti, Matteo, Probing allosteric communication with combined molecular dynamics simulations and network analysis, «CURRENT OPINION IN STRUCTURAL BIOLOGY», 2024, 86, pp. 1 - 10 [Scientific article]Open Access
Romano, M.; Falchi, F.; De Gregorio, E.; Stabile, M.; Migliaccio, A.; Ruggiero, A.; Napolitano, V.; Autiero, I.; Squeglia, F.; Berisio, R., Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii, «FRONTIERS IN MICROBIOLOGY», 2024, 15, pp. 1 - 12 [Scientific article]Open Access
Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea, Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5, «JOURNAL OF MEDICINAL CHEMISTRY», 2023, 66, pp. 9797 - 9822 [Scientific article]Open Access
Bagnolini, G.; Falchi, F.; Sdei, F.; Roberti, M.; Sosic, A.; Sissi, C.; Bolognesi, M. L., Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs), in: Book of abstract, 2023(atti di: XXVIII National Meeting on Medicinal Chemistry (NMMC28), Chieti, 17-20 September 2023) [Poster]
Brusa I.; Sondo E.; Falchi F.; Pedemonte N.; Roberti M.; Cavalli A., Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 5212 - 5243 [Scientific article]Open Access
Ghassabian H.; Falchi F.; Timmoneri M.; Mercorelli B.; Loregian A.; Palu G.; Alvisi G., Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication, «VIRUSES», 2021, 13, Article number: 941 , pp. 941 - 941 [Scientific article]Open Access
Barone M.; Rampelli S.; Biagi E.; Bertozzi S.M.; Falchi F.; Cavalli A.; Armirotti A.; Brigidi P.; Turroni S.; Candela M., Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2021, 64, pp. 17277 - 17286 [Scientific article]Open Access
Bagnolini G.; Milano D.; Manerba M.; Schipani F.; Ortega J.A.; Gioia D.; Falchi F.; Balboni A.; Farabegoli F.; De Franco F.; Robertson J.; Pellicciari R.; Pallavicini I.; Peri S.; Minucci S.; Girotto S.; Di Stefano G.; Roberti M.; Cavalli A., Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 2588 - 2619 [Scientific article]Open Access
Masetti, Matteo; Falchi, Federico; Gioia, Dario; Recanatini, Maurizio; Ciurli, Stefano; Musiani, Francesco, Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation, «MOLECULES», 2020, 25, Article number: 2911 , pp. 1 - 21 [Scientific article]Open Access
Marinella Roberti, Fabrizio Schipani, Greta Bagnolini, Domenico Milano, Elisa Giacomini, Federico Falchi, Andrea Balboni, Marcella Manerba, Fulvia Farabegoli, Francesca De Franco, Janet Robertson, Saverio Minucci, Isabella Pallavicini, Giuseppina Di Stefano, Stefania Girotto, Roberto Pellicciari, and Andrea Cavalli, Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with
Olaparib in Pancreatic Cancer Cells, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 165, pp. 80 - 92 [Scientific article]
Vedove A.D.; Falchi F.; Donini S.; Dobric A.; Germain S.; Martino G.P.D.; Prosdocimi T.; Vettraino C.; Torretta A.; Cavalli A.; Rigot V.; Andre F.; Parisini E., Structure-based virtual screening allows the identification of efficient modulators of E-cadherin-mediated cell-cell adhesion, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2019, 20, Article number: 3404 , pp. 1 - 17 [Scientific article]
Sondo, Elvira; Falchi, Federico; Caci, Emanuela; Ferrera, Loretta; Giacomini, Elisa; Pesce, Emanuela; Tomati, Valeria; Mandrup Bertozzi, Sine; Goldoni, Luca; Armirotti, Andrea; Ravazzolo, Roberto; Cavalli, Andrea; Pedemonte, Nicoletta, Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia, «CELL CHEMICAL BIOLOGY», 2018, 25, pp. 891 - 905 [Scientific article]
