Sdei, F.; Bagnolini, G.; Falchi, F.; Sosic, A.; Fabbian, S.; Duca, M.; Bolognesi, M. L., Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21, in: 1, 2025, pp. 1 - 1 (atti di: XXXII Young Research Fellows Meeting, Paris, February 2025) [Contributo in Atti di convegno]
Masi, Mirco; Poppi, Laura; Previtali, Viola; Nelson, Shannon R; Wynne, Kieran; Varignani, Giulia; Falchi, Federico; Veronesi, Marina; Albanesi, Ennio; Tedesco, Daniele; De Franco, Francesca; Ciamarone, Andrea; Myers, Samuel H; Ortega, Jose Antonio; Bagnolini, Greta; Ferrandi, Giovanni; Farabegoli, Fulvia; Tirelli, Nicola; Di Stefano, Giuseppina; Oliviero, Giorgio; Walsh, Naomi; Roberti, Marinella; Girotto, Stefania; Cavalli, Andrea, Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity, «CELL DEATH DISCOVERY», 2025, 11, pp. 1 - 23 [articolo]
Romeo, E.; Saccoliti, F.; Ocello, R.; Andonaia, A.; Allegretta, C.; Pastorino, C.; Pedemonte, N.; Falchi, F.; Laselva, O.; Bandiera, T.; Bertozzi, F., Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Potent CFTR Corrector, «JOURNAL OF MEDICINAL CHEMISTRY», 2025, 68, pp. 4596 - 4618 [articolo]
Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Falchi, Federico; Previtali, Viola; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors
to trigger synthetic lethality with Olaparib in pancreatic cancer cells, in: National Congress of the Italian Chemistry Society 2024, 2024(atti di: SCI 2024 Chemistry ELEMENTS OF FUTURE, Milano, 26th August 2024) [atti di convegno-poster]
Sdei, F.; Bagnolini, G.; Falchi, F.; Sosic, A.; Bolognesi, M. L., DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETING PRE-MIRNA21 TOWARD THE DEVELOPMENT OF RIBONUCLEASE TARGETING CHIMERAS (RIBOTACS) TO REGULATE THE ONCOGENIC MIRNA21, in: 1, 2024, pp. 1 - 1 (atti di: XXIII Giornata della chimica dell'Emilia-Romagna 2024, Modena, 19 December 2024) [Contributo in Atti di convegno]
Previtali, Viola; Masi, Mirco; Poppi, Laura; Varignani, Giulia; Falchi, Federico; Tedesco, Daniele; Wynne, Kieran; Oliviero, Giorgio; Bagnolini, Greta; Farabegoli, Fulvia; DI STEFANO, Giuseppina; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea, Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer, in: 1, 2024(atti di: EFMC ISMC XXVIII EFMC International Symposium on Medicinal Chemistry, Rome, 1-5 September 2024) [atti di convegno-poster]
Bernetti, Mattia; Bosio, Stefano; Bresciani, Veronica; Falchi, Federico; Masetti, Matteo, Probing allosteric communication with combined molecular dynamics simulations and network analysis, «CURRENT OPINION IN STRUCTURAL BIOLOGY», 2024, 86, pp. 1 - 10 [articolo]Open Access
Romano, M.; Falchi, F.; De Gregorio, E.; Stabile, M.; Migliaccio, A.; Ruggiero, A.; Napolitano, V.; Autiero, I.; Squeglia, F.; Berisio, R., Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii, «FRONTIERS IN MICROBIOLOGY», 2024, 15, pp. 1 - 12 [articolo]Open Access
Sdei, Federico; Bagnolini, Greta; Falchi, Federico; Ghezzo, M.; Sosic, Alice; Sissi, Claudia; Roberti, Marinella; Bolognesi, MARIA LAURA, Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs), in: 1, 2024(atti di: XXVIII Congresso Nazionale della Società Chimica Italiana - Elementi di Futuro, Milan, 26-30 August 2024) [atti di convegno-poster]
Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea, Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5, «JOURNAL OF MEDICINAL CHEMISTRY», 2023, 66, pp. 9797 - 9822 [articolo]Open Access
Bagnolini, G.; Falchi, F.; Sdei, F.; Roberti, M.; Sosic, A.; Sissi, C.; Bolognesi, M. L., Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs), in: Book of abstract, 2023(atti di: XXVIII National Meeting on Medicinal Chemistry (NMMC28), Chieti, 17-20 September 2023) [atti di convegno-poster]
Brusa I.; Sondo E.; Falchi F.; Pedemonte N.; Roberti M.; Cavalli A., Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 5212 - 5243 [articolo]Open Access
Ghassabian H.; Falchi F.; Timmoneri M.; Mercorelli B.; Loregian A.; Palu G.; Alvisi G., Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication, «VIRUSES», 2021, 13, Article number: 941, pp. 941 - 941 [articolo]Open Access
Barone M.; Rampelli S.; Biagi E.; Bertozzi S.M.; Falchi F.; Cavalli A.; Armirotti A.; Brigidi P.; Turroni S.; Candela M., Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2021, 64, pp. 17277 - 17286 [articolo]Open Access
Bagnolini G.; Milano D.; Manerba M.; Schipani F.; Ortega J.A.; Gioia D.; Falchi F.; Balboni A.; Farabegoli F.; De Franco F.; Robertson J.; Pellicciari R.; Pallavicini I.; Peri S.; Minucci S.; Girotto S.; Di Stefano G.; Roberti M.; Cavalli A., Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 2588 - 2619 [articolo]Open Access
