Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHEM-07/A Chimica farmaceutica

Coordinatrice del Corso di Dottorato in Scienze biotecnologiche, biocomputazionali, farmaceutiche e farmacologiche

Pubblicazioni

Maria, Bolognesi, Targeting GAPDH with small molecule inhibitors: 2-phenoxynaphthoquinones as lead candidates for Trypanosomatid diseases, in: ICC-04 - The Fourth International Conference on Cofactors, 2014, pp. 13 - 13 (atti di: 4th International Conference on Cofactors, Parma, Casa della Musica, 25th -28th August 2014,) [Contributo in Atti di convegno]

Federica Belluti;Elisa Uliassi;Giacomo Veronesi;Christian Bergamini;Marcel Kaiser;Reto Brun;Angelo Viola;Romana Fato;Paul A. M. Michels;R. Luise Krauth-Siegel;Andrea Cavalli;Maria Laura Bolognesi, Toward the Development of Dual-Targeted Glyceraldehyde-3-phosphate Dehydrogenase/Trypanothione Reductase Inhibitors againstTrypanosoma bruceiandTrypanosoma cruzi, «CHEMMEDCHEM», 2014, 9, pp. 371 - 382 [articolo]

F. Prati;E. Uliassi;M. L. Bolognesi, Two diseases, one approach: multitarget drug discovery in Alzheimer's and neglected tropical diseases, «MEDCHEMCOMM», 2014, 5, pp. 853 - 861 [articolo]

Staderini, M; Aulic, S; Bartolini, M; Hoang, NAT; Gonzalez-Ruiz, V; Perez, DI; Cabezas, N; Martinez, A; Martin, MA; Andrisano; Legname, G; Menendez, JC; Bolognesi, ML, A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases, «ACS MEDICINAL CHEMISTRY LETTERS», 2013, 4, pp. 225 - 229 [articolo]

Bolognesi, Maria Laura, Amyloid Chemical Probes and Theranostics: Steps Toward Personalized Medicine in Neurodegenerative DiseasesMedicinal Chemistry Approaches to Personalized Medicine, in: Karen Lackey, Bruce D. Roth, Methods and Principles in Medicinal ChemistryMedicinal Chemistry Approaches to Personalized Medicine, Weinheim, Wiley-VCH Verlag GmbH & Co. KGaA, 2013, pp. 211 - 226 [capitolo di libro]

Federica Belluti;Remo Perozzo;Leonardo Lauciello;Francesco Colizzi;Dirk Kostrewa;Alessandra Bisi;Silvia Gobbi;Angela Rampa;Maria Laura Bolognesi;Maurizio Recanatini;Reto Brun;Leonardo Scapozza;Andrea Cavalli, Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors ofPlasmodium falciparumEnoyl-ACP-reductase (PfFabI), «JOURNAL OF MEDICINAL CHEMISTRY», 2013, 56, pp. 7516 - 7526 [articolo]

Giuseppe Legname;Maria Bolognesi, Editorial (Thematic Issue: Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics), «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2013, 13, pp. 2395 - 2396 [replica/breve intervento]

Matteo Staderini;Giuseppe Legname;Maria Bolognesi;J. Menéndez, Modulation of Prion by Small Molecules: From Monovalent to Bivalent and Multivalent Ligands, «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2013, 13, pp. 2491 - 2503 [articolo]

Anna Minarini; Andrea Milelli; Elena Simoni; Michela Rosini; Maria Laura Bolognesi; Chiara Marchetti; Vincenzo Tumiatti, Multifunctional Tacrine Derivatives in Alzheimer’s Disease, «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2013, 13, pp. 1771 - 1786 [articolo]

Simone Pieretti;Jurgen R. Haanstra;Muriel Mazet;Remo Perozzo;Christian Bergamini;Federica Prati;Romana Fato;Giorgio Lenaz;Giovanni Capranico;Reto Brun;Barbara M. Bakker;Paul A. M. Michels;Leonardo Scapozza;Maria Laura Bolognesi;Andrea Cavalli, Naphthoquinone Derivatives Exert Their Antitrypanosomal Activity via a Multi-Target Mechanism, «PLOS NEGLECTED TROPICAL DISEASES», 2013, 7, pp. e2012 - e2023 [articolo]

Valeria Capurro;Perrine Busquet;Joao Pedro Lopes;Rosalia Bertorelli;Glauco Tarozzo;Maria Laura Bolognesi;Daniele Piomelli;Angelo Reggiani;Andrea Cavalli, Pharmacological Characterization of Memoquin, a Multi-Target Compound for the Treatment of Alzheimer's Disease, «PLOS ONE», 2013, 8, pp. e56870 - e56877 [articolo]

M. L. Bolognesi, Polypharmacology in a Single Drug: Multitarget Drugs, «CURRENT MEDICINAL CHEMISTRY», 2013, 20, pp. 1639 - 1645 [articolo]

Federica Prati;Manuela Bartolini;Elena Simoni;Angela De Simone;Antonella Pinto;Vincenza Andrisano;Maria Laura Bolognesi, Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2013, 23, pp. 6254 - 6258 [articolo]

Suzana Aulić;Maria Laura Bolognesi;Giuseppe Legname, Small-Molecule Theranostic Probes: A Promising Future in Neurodegenerative Diseases, «INTERNATIONAL JOURNAL OF CELL BIOLOGY», 2013, 2013, Article number: Article ID 150952, pp. 1 - 19 [articolo]

M. Staderini; N. Cabezas; M. L. Bolognesi; J. Carlos Menéndez, Solvent- and chromatography-free amination of pi-deficient nitrogen heterocycles under microwave irradiation. A fast, efficient and green route to 9-aminoacridines, 4-aminoquinolines and 4-aminoquinazolines and its application to the synthesis of the drugs amsacrine and bistacrine, «TETRAHEDRON», 2013, 69, pp. 1024 - 1030 [articolo]