Foto del docente

Maria Laura Bolognesi

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHEM-07/A Chimica farmaceutica

Coordinatrice del Corso di Dottorato in Scienze biotecnologiche, biocomputazionali, farmaceutiche e farmacologiche

Pubblicazioni

Prati F;De Simone A;Bisignano P;Armirotti A;Summa M;Pizzirani D;Scarpelli R;Perez DI;Andrisano V;Perez-Castillo A;Monti B;Massenzio F;Polito L;Racchi M;Favia AD;Bottegoni G;Martinez A;Bolognesi ML;Cavalli A, Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors., «ANGEWANDTE CHEMIE. INTERNATIONAL EDITION», 2015, 54, pp. 1578 - 1582 [articolo]

Benchekroun, M.; Bartolini, M.; Egea, J.; Romero, A.; Soriano, E.; Pudlo, M.; Luzet, V.; Andrisano, V.; Jimeno, M.-L.; Lopez, M.G.; Wehle, S.; Gharbi, T.; Refouvelet, B.; De Andres, L.; Herrera-Arozamena, C.; Monti, B.; Bolognesi, M.L.; Rodriguez-Franco, M.I.; Decker, M.; Marco-Contelles, J.; Ismaili, L., Novel tacrine-grafted ugi adducts as multipotent anti-alzheimer drugs: A synthetic renewal in tacrine-ferulic acid hybrids, «CHEMMEDCHEM», 2015, 10, pp. 523 - 539 [articolo]

De Vin, Filip; Choi, Sze Men; Bolognesi, Maria L.; Lefebvre, Romain A, Presynaptic M3 muscarinic cholinoceptors mediate inhibition of excitatory synaptic transmission in area CA1 of rat hippocampus, «BRAIN RESEARCH», 2015, 1629, pp. 260 - 269 [articolo]

Bolognesi, Maria Laura; Bongarzone, Salvatore; Aulic, Suzana; Ai Tran, Hoang Ngoc; Prati, Federica; Carloni, Paolo; Legname, Giuseppe, Rational approach to an antiprion compound with a multiple mechanism of action, «FUTURE MEDICINAL CHEMISTRY», 2015, 7, pp. 2113 - 2120 [articolo]

Prati, F.; Bolognesi, M. L, Tackling neurodegeneration with multi-target and theranostic small molecules, in: 2015 Medicinal Chemistry Reviews, Washington,, ACS Division of Medicinal Chemistry, 2015, pp. 347 - 356 [capitolo di libro]

Santucci, Matteo; Vignudelli, Tatiana; Ferrari, Stefania; Mor, Marco; Scalvini, Laura; Bolognesi, Maria Laura; Uliassi, Elisa; Costi, Maria Paola, The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment, «JOURNAL OF MEDICINAL CHEMISTRY», 2015, 58, pp. 4857 - 4873 [articolo]

Prati, Federica; Bergamini, Christian; Molina, Maria Teresa; Falchi, Federico; Cavalli, Andrea; Kaiser, Marcel; Brun, Reto; Fato, Romana; Bolognesi, Maria Laura, 2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile, «JOURNAL OF MEDICINAL CHEMISTRY», 2015, 58, pp. 6422 - 6434 [articolo]

Prati, Federica; De Simone, Angela; Armirotti, Andrea; Summa, Maria; Pizzirani, Daniela; Scarpelli, Rita; Bertozzi, Sine Mandrup; Perez, Daniel I.; Andrisano, Vincenza; Perez-Castillo, Ana; Monti, Barbara; Massenzio, Francesca; Polito, Letizia; Racchi, Marco; Sabatino, Piera; Bottegoni, Giovanni; Martinez, Ana; Cavalli, Andrea; Bolognesi, Maria L., 3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease, «ACS CHEMICAL NEUROSCIENCE», 2015, 6, pp. 1665 - 1682 [articolo]Open Access

Maria, Bolognesi, Biotecnologie e scoperta dei farmaci, in: Chimica organica medica e farmaceutica, Rozzano Milano, Zanichelli Editore spa, 2014, pp. 119 - 154 . Opera originale: Autore: John M. Beale, Jr. - Titolo: Biotechnology and drug discovery [contributo in volume (traduzione)]

Eugenie Nepovimova;Elisa Uliassi;Jan Korabecny;Luis Emiliano Peña-Altamira;Sarah Samez;Alessandro Pesaresi;Gregory E. Garcia;Manuela Bartolini;Vincenza Andrisano;Christian Bergamini;Romana Fato;Doriano Lamba;Marinella Roberti;Kamil Kuca;Barbara Monti;Maria Laura Bolognesi, Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects, «JOURNAL OF MEDICINAL CHEMISTRY», 2014, 57, pp. 8576 - 8589 [articolo]

Salvatore Bongarzone;Matteo Staderini;Maria Laura Bolognesi, Multitarget ligands and theranostics: sharpening the medicinal chemistry sword against prion diseases, «FUTURE MEDICINAL CHEMISTRY», 2014, 6, pp. 1017 - 1029 [articolo]

Federica Prati; Maria Laura Bolognesi, PHENOTYPIC HITS IN ANTI-TRYPANOSOMA DRUG DISCOVERY, «LA CHIMICA E L'INDUSTRIA», 2014, XCVI, pp. 46 - 47 [articolo]

Bhaskar Saha;Federica Prati;Adele Goldman-Pinkovich;Federica Lizzi;Federica Belluti;Roni Koren;Dan Zilberstein;Maria Laura Bolognesi, Quinone-Amino Acid Conjugates Targeting Leishmania Amino Acid Transporters, «PLOS ONE», 2014, 9, pp. e107994 - e107994 [articolo]

Maria Laura, Bolognesi, Rationally designining multitarget directed ligands against neurodegeneration, in: 5th International Conference on the Development of Biomedical Engineering, Vo Van Toi and Tran HaLien Phuong, 2014, pp. 41 - 41 (atti di: 5th International Conference on Biomedical Engineering in Vietnam, Ho Chi Minh City, June 16-18 2014) [Contributo in Atti di convegno]

Bolognesi ML; Bergamini C; Fato R; Oiry J; Vasseur JJ; Smietana M., Synthesis of new lipoic acid conjugates and evaluation of their free radical scavenging and neuroprotective activities, «CHEMICAL BIOLOGY & DRUG DESIGN», 2014, 83, pp. 688 - 696 [articolo]