Foto del docente

Letizia Pruccoli

Adjunct professor

Department for Life Quality Studies

Research fellow

Department for Life Quality Studies

Teaching tutor

Department of Chemistry "Giacomo Ciamician"

Publications

Mesquita Campos, Hericles; Mota Pereira, Robbert; Yasmin de Oliveira Ferreira, Pamela; Uchenna, Nkaa; Rio Branco da Silva, Cínthia; Pruccoli, Letizia; Sanz, German; Ferreira Rodrigues, Marcella; Gontijo Vaz, Boniek; Gonçalves Rivello, Barbara; Luís Batista da Rocha, Andre; Silva de Carvalho, Flavio; de Almeida Ribeiro Oliveira, Gerlon; Morais Liao, Luciano; de Castro Georg, Raphaela; Alves Leite, Jacqueline; Cristina Alcantara dos Santos, Fernanda; Alves Costa, Elson; Menegatti, Ricardo; Tarozzi, Andrea; Cesar Ghedini, Paulo, A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models, «CHEMICO-BIOLOGICAL INTERACTIONS», 2024, 395, Article number: 111026 , pp. 1 - 10 [Scientific article]

Pruccoli, Letizia; Nicolini, Benedetta; Lianza, Mariacaterina; Teti, Gabriella; Falconi, Mirella; Tarozzi, Andrea; Antognoni, Fabiana, Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells, «PLANTS», 2024, 13, Article number: 808 , pp. 1 - 9 [Scientific article]Open Access

Pruccoli, Letizia; Balducci, Martina; Pagliarani, Barbara; Tarozzi, Andrea, Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study, «CURRENT ISSUES IN MOLECULAR BIOLOGY», 2024, 46, pp. 5984 - 5998 [Scientific article]Open Access

Pereira, R. M.; Campos, H. M.; de Oliveira Ferreira, P. Y.; Uchenna, N.; Silva, Y. S.; Okoh, V. I.; Pruccoli, L.; Arruda, E. L.; Liao, L. M.; Mota, P. A. A.; Leite, J. A.; de Castro Georg, R.; Damatta, D.; dos Santos, F. C. A.; Costa, E. A.; Tarozzi, A.; Menegatti, R.; Ghedini, P. C., Glycosylation of chrysin with β-d-glucose tetraacetate (LQFM280) enhances its in vitro and in vivo neuroprotective effects against the toxicity induced by 3-nitropropionic acid, «NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY», 2024, Oct 16, pp. 1 - 15 [Scientific article]

de Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Letizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro de Souza, Hygor M.; Tarozzi, Andrea; Silva Gontijo, Vanessa; Jr., Claudio Viegas, Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease, «BIOORGANIC CHEMISTRY», 2024, 150, Article number: 107587 , pp. 1 - 18 [Scientific article]

Balducci M.; Pruccoli L.; Tarozzi A., Heat stress as a potential risk factor for vitamin D deficiency, «MEDICAL HYPOTHESES», 2023, 176, Article number: 111085 , pp. 1 - 3 [Scientific article]Open Access

Zuccarini M.; Pruccoli L.; Balducci M.; Giuliani P.; Caciagli F.; Ciccarelli R.; Di Iorio P., Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions, «JOURNAL OF CLINICAL MEDICINE», 2023, 12, Article number: 1172 , pp. 1 - 17 [Scientific article]Open Access

Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A., PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease, «ACS CHEMICAL NEUROSCIENCE», 2023, 14, pp. 1963 - 1970 [Scientific article]Open Access

De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena, Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 252, Article number: 115297 , pp. 1 - 15 [Scientific article]Open Access

Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr, Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation, «RSC MEDICINAL CHEMISTRY», 2022, 13, pp. 568 - 584 [Scientific article]Open Access

Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V.; Bolognesi, M. L.; Tarozzi, A.; Milelli, A., PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION, in: XXVII National Meeting on Medicinal Chemistry, 2022, pp. 160 - 160 (atti di: XXVII National Meeting on Medicinal Chemistry, Bari, 11-14 settembre 2022) [Poster]

Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Pruccoli L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C., Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies, «TOXICOLOGY», 2022, 465, Article number: 153033 , pp. 1 - 13 [Scientific article]Open Access

Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimaraes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr., Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease, «BIOORGANIC & MEDICINAL CHEMISTRY», 2022, 71, Article number: 116952 , pp. 1 - 11 [Scientific article]Open Access

Gigliobianco, M. R.; Cortese, M.; Peregrina, D. V.; Villa, C.; Lupidi, G.; Pruccoli, L.; Angeloni, C.; Tarozzi, A.; Censi, R.; Di Martino, P., Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations, «COSMETICS», 2021, 8, Article number: 51 , pp. 1 - 18 [Scientific article]Open Access

Fazzina, Martina; Pruccoli, Letizia; Tarozzi, Andrea; Massenzio, Francesca; Monti, Barbara; Maestri, Davide; Bergonzoni, Matteo; Frabetti, Flavia; Casadei, Raffaella, Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease, in: 2nd International Conference on Neuroprotection by Drugs, Nutraceuticals, and Physical Activity, 2021, pp. 35 - 35 (atti di: 2nd International Conference on Neuroprotection by Drugs, Nutraceuticals, and Physical Activity, Virtual edition, 9-10 dicembre 2021) [Abstract]

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