Foto del docente

Anna Maria Ghelli

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIOS-07/A Biochemistry

Publications

Tropeano, C. V.; La Morgia, C.; Achilli, A.; Iommarini, L.; Tioli, G.; Caporali, L.; Olivieri, A.; Valentino, M. L.; Liguori, R.; Barboni, P.; Martinuzzi, A.; Tonon, C.; Lodi, R.; Torroni, A.; Carelli, V.; Ghelli, A. M., Adult Leigh Syndrome Associated with the m.15635T>C Mitochondrial DNA Variant Affecting the Cytochrome b (MT-CYB) Gene, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2025, 26, Article number: 1116 , pp. 1116 - 1116 [Scientific article]

Liang, C.; Padavannil, A.; Zhang, S.; Beh, S.; Robinson, D. R. L.; Meisterknecht, J.; Cabrera-Orefice, A.; Koves, T. R.; Watanabe, C.; Watanabe, M.; Illescas, M.; Lim, R.; Johnson, J. M.; Ren, S.; Wu, Y. J.; Kappei, D.; Ghelli, A. M.; Funai, K.; Osaka, H.; Muoio, D.; Ugalde, C.; Wittig, I.; Stroud, D. A.; Letts, J. A.; Ho, L., Formation of I2+III2 supercomplex rescues respiratory chain defects, «CELL METABOLISM», 2025, 37, pp. 441 - 459 [Scientific article]

Miglietta, Stefano; Sollazzo, Manuela; Gherardi, Iacopo; Milioni, Sara; Cavina, Beatrice; Marchio, Lorena; De Luise, Monica; Coada, Camelia Alexandra; Fiorillo, Marco; Perrone, Anna Myriam; Kurelac, Ivana; Gasparre, Giuseppe; Iommarini, Luisa; Ghelli, Anna Maria; Porcelli, Anna Maria, Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells, «OPEN BIOLOGY», 2025, 15, Article number: :240151 , pp. 1 - 12 [Scientific article]Open Access

Rigobello L.; Lugli F.; Caporali L.; Bartocci A.; Fadanni J.; Zerbetto F.; Iommarini L.; Carelli V.; Ghelli A.M.; Musiani F., A computational study to assess the pathogenicity of single or combinations of missense variants on respiratory complex I, «INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES», 2024, 273, Article number: 133086 , pp. 1 - 15 [Scientific article]Open Access

Tioli, G; Musiani, F; Iommarini, L; Porcelli, Am; Carelli, V; Ghelli, Am, Biochemical and computational approaches to dissect the effect of MT-CYB pathogenic mutations on respiratory chain activity and assembly, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2024, 1865, pp. 116 - 116 [Abstract]

Aleo S.J.; Del Dotto V.; Romagnoli M.; Fiorini C.; Capirossi G.; Peron C.; Maresca A.; Caporali L.; Capristo M.; Tropeano C.V.; Zanna C.; Ross-Cisneros F.N.; Sadun A.A.; Pignataro M.G.; Giordano C.; Fasano C.; Cavaliere A.; Porcelli A.M.; Tioli G.; Musiani F.; Catania A.; Lamperti C.; Marzoli S.B.; De Negri A.; Cascavilla M.L.; Battista M.; Barboni P.; Carbonelli M.; Amore G.; La Morgia C.; Smirnov D.; Vasilescu C.; Farzeen A.; Blickhaeuser B.; Prokisch H.; Priglinger C.; Livonius B.; Catarino C.B.; Klopstock T.; Tiranti V.; Carelli V.; Ghelli A.M., Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy, «CELL REPORTS MEDICINE», 2024, 5, Article number: 101383 , pp. 1 - 24 [Scientific article]Open Access

Stefano Miglietta; Manuela Sollazzo; Iacopo Gherardi; Sara Milioni; Beatrice Cavina; Lorena Marchio; Monica De Luise; Camelia Alexandra Coada; Marco Fiorillo; Anna Myriam Perrone; Ivana Kurelac; Giuseppe Gasparre; Luisa Iommarini; Anna Maria Ghelli; Anna Maria Porcelli, Mitochondrial Chaperonin MCJ Promotes Vulnerability to Ferroptosis of Chemoresistant Ovarian Cancer Cells – Dataset, 2024. [Database]

Milioni, S; Sollazzo, M; Zanna, C; Kurelac, I; Tartagni, O; Gherardi, I; Ghelli, Am; Filho, Adc; Schulze, A; Gasparre, G; Porcelli, Am; Iommarini, L, Respiratory complex I deficiency triggers OMA1-mediated integrated stress response and affects lipid homeostasis during glucose restriction, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2024, 1865, pp. 123 - 124 [Abstract]

Bin, Tancredi; Venturoli, Giovanni; Ghelli, Anna Maria; Francia, Francesco, Use of bacterial photosynthetic vesicles to evaluate the effect of ionic liquids on the permeability of biological membranes, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES», 2024, 1866, pp. 184291 - 184300 [Scientific article]Open Access

De Luise, Monica; Sollazzo, Manuela; Lama, Eleonora; Coadă, Camelia Alexandra; Bressi, Licia; Iorio, Maria; Cavina, Beatrice; D’Angelo, Luigi; Milioni, Sara; Marchio, Lorena; Miglietta, Stefano; Coluccelli, Sara; Tedesco, Greta; Ghelli, Anna; Lemma, Silvia; Perrone, Anna Myriam; Kurelac, Ivana; Iommarini, Luisa; Porcelli, Anna Maria; Gasparre, Giuseppe, Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer, «SCIENTIFIC REPORTS», 2022, 12, Article number: 8020 , pp. 1 - 12 [Scientific article]Open Access

Stefano Miglietta, Manuela Sollazzo, Lorena Marchio, Iacopo Gherardi, Sara Milioni, Luisa Iommarini, Ivana Kurelac, Anna Maria Ghelli, Giuseppe Gasparre, Anna Maria Porcelli, MCJ/DNAJC15 mitochondrial chaperone as a metabolic “balance needle” in ovarian cancer chemoresistance, in: MCJ/DNAJC15 mitochondrial chaperone as a metabolic “balance needle” in ovarian cancer chemoresistance, 2022, pp. 0 - 1 (atti di: 1st Workshop of the SIB group «Tumor Biochemistry», From genes to metabolites through proteins: dealing with human health and disease., Milan (Italy), 25/02/2022) [Contribution to conference proceedings]

Miglietta, Stefano; Girolimetti, Giulia; Marchio, Lorena; Sollazzo, Manuela; Laprovitera, Noemi; Coluccelli, Sara; De Biase, Dario; De Leo, Antonio; Santini, Donatella; Kurelac, Ivana; Iommarini, Luisa; Ghelli, Anna; Campana, Davide; Ferracin, Manuela; Perrone, Anna Myriam; Gasparre, Giuseppe; Porcelli, Anna Maria, MicroRNA and Metabolic Profiling of a Primary Ovarian Neuroendocrine Carcinoma Pulmonary-Type Reveals a High Degree of Similarity with Small Cell Lung Cancer, «NON-CODING RNA», 2022, 8, Article number: 64 , pp. 1 - 13 [Scientific article]Open Access

Kurelac, Ivana; Cavina, Beatrice; Sollazzo, Manuela; Miglietta, Stefano; Fornasa, Agnese; De Luise, Monica; Iorio, Maria; Lama, Eleonora; Traversa, Daniele; Nasiri, Hamid Razi; Ghelli, Anna; Musiani, Francesco; Porcelli, Anna Maria; Iommarini, Luisa; Gasparre, Giuseppe, NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors, «OPEN BIOLOGY», 2022, 12, Article number: 220198 , pp. 1 - 16 [Scientific article]Open Access

Musiani F.; Rigobello L.; Iommarini L.; Carelli V.; Esposti M.D.; Ghelli A.M., New Insights on Rotenone Resistance of Complex I Induced by the m.11778G>A/MT-ND4 Mutation Associated with Leber’s Hereditary Optic Neuropathy, «MOLECULES», 2022, 27, Article number: 1341 , pp. 1341 - 1350 [Scientific article]Open Access

Iommarini, Luisa; Kurelac, Ivana; Cavina, Beatrice; Fornasa, Agnese; Traversa, Daniele; Iorio, Maria; Sollazzo, Manuela; De Luise, Monica; Lama, Eleonora; Nasiri, Hamid Razi; Ghelli, Anna; Musiani, Francesco; Gasparre, Giuseppe; Porcelli, Anna Maria, Respiratory complex I null cancer cells and molecular docking reveal specificity and mode of action inhibitors with anticancer activity, in: Volume 1863, Supplement, «BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS», 2022, 1863, pp. 148637 - 148637 (atti di: 21st European Bioenergetics Conference (EBEC), Aix en Provence, France, 20-25/08/2022) [Abstract]

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