Gennaccaro L.; Fuchs C.; Loi M.; Pizzo R.; Alvente S.; Berteotti C.; Lupori L.; Sagona G.; Galvani G.; Gurgone A.; Raspanti A.; Medici G.; Tassinari M.; Trazzi S.; Ren E.; Rimondini R.; Pizzorusso T.; Zoccoli G.; Giustetto M.; Ciani E., Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death, «AGING AND DISEASE», 2021, 12, pp. 764 - 785 [articolo]Open Access
Nicola Mottolese, Giuseppe Galvani, Laura Gennaccaro, Manuela Loi, Giorgio Medici, Marianna Tassinari, Stefania Trazzi, Elisabetta Ciani, Inhibition of microglia over-activation restores neuronal survival and maturation in a mouse model of CDKL5 deficiency disorder, in: N. Mottolese, G. Galvani, L. Gennaccaro, M. Loi, G. Medici, M. Tassinari, S. Trazzi, E. Ciani, Proceedings NWG 2021, 2021(atti di: Göttingen Meeting of the German Neuroscience Society, Göttingen, German, 2021) [atti di convegno-poster]
Galvani, Giuseppe; Mottolese, Nicola; Gennaccaro, Laura; Loi, Manuela; Medici, Giorgio; Tassinari, Marianna; Fuchs, Claudia; Ciani, Elisabetta; Trazzi, Stefania, Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder, «JOURNAL OF NEUROINFLAMMATION», 2021, 18, Article number: 155, pp. 1 - 21 [articolo]Open Access
Loi, Manuela; Gennaccaro, Laura; Fuchs, Claudia; Trazzi, Stefania; Medici, Giorgio; Galvani, Giuseppe; Mottolese, Nicola; Tassinari, Marianna; Giorgini, Roberto Rimondini; Milelli, Andrea; Ciani, Elisabetta, Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2021, 22, Article number: 5950, pp. 1 - 24 [articolo]Open Access
Anna Cecilia Berardi, Claudia Fuchs, Laura Gennaccaro, Vincenzo Roncacè, Yassine Aitbali,
Elisa Ren, Stefania Trazzi, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani, Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist, in: FENS 2020 e-Posters, 2020(atti di: FENS 2020, Virtual, 11-15 july 2020) [atti di convegno-poster]
Loi M.; Trazzi S.; Fuchs C.; Galvani G.; Medici G.; Gennaccaro L.; Tassinari M.; Ciani E., Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons, «MOLECULAR NEUROBIOLOGY», 2020, 30, pp. 12035 - 12054 [articolo]
Fuchs C.; Gennaccaro L.; Ren E.; Galvani G.; Trazzi S.; Medici G.; Loi M.; Conway E.; Devinsky O.; Rimondini R.; Ciani E., Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder, «NEUROPHARMACOLOGY», 2020, 167, Article number: 107746, pp. 107746 - 107764 [articolo]
Trovo L.; Fuchs C.; De Rosa R.; Barbiero I.; Tramarin M.; Ciani E.; Rusconi L.; Kilstrup-Nielsen C., The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo, «NEUROBIOLOGY OF DISEASE», 2020, 138, Article number: 104791, pp. 104791 - 104803 [articolo]Open Access
Fuchs C.; Medici G.; Trazzi S.; Gennaccaro L.; Galvani G.; Berteotti C.; Ren E.; Loi M.; Ciani E., CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019), «BRAIN PATHOLOGY», 2019, 29, pp. 658 - 674 [articolo]
Ren E.; Roncace V.; Trazzi S.; Fuchs C.; Medici G.; Gennaccaro L.; Loi M.; Galvani G.; Ye K.; Rimondini R.; Aicardi G.; Ciani E., Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist, «FRONTIERS IN CELLULAR NEUROSCIENCE», 2019, 13, Article number: 169, pp. 1 - 15 [articolo]Open Access
Lupori L.; Sagona G.; Fuchs C.; Mazziotti R.; Stefanov A.; Putignano E.; Napoli D.; Strettoi E.; Ciani E.; Pizzorusso T., Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder, «HUMAN MOLECULAR GENETICS», 2019, 28, pp. 2851 - 2861 [articolo]Open Access
Trazzi, Stefania; De Franceschi, Marianna; Fuchs, Claudia; Bastianini, Stefano; Viggiano, Rocchina; Lupori, Leonardo; Mazziotti, Raffaele; Medici, Giorgio; Martire, Viviana Lo; Ren, Elisa; Rimondini, Roberto; Zoccoli, Giovanna; Bartesaghi, Renata; Pizzorusso, Tommaso; Ciani, Elisabetta*, CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder, «HUMAN MOLECULAR GENETICS», 2018, 27, pp. 1572 - 1592 [articolo]Open Access
Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Martire, Viviana Lo; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta*, Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder, «NEURAL PLASTICITY», 2018, 2018, Article number: 9726950, pp. 1 - 18 [articolo]Open Access
Fuchs, Claudia; Gennaccaro, Laura; Trazzi, Stefania; Bastianini, Stefano; Bettini, Simone; Lo Martire, Viviana; Ren, Elisa; Medici, Giorgio; Zoccoli, Giovanna; Rimondini, Roberto; Ciani, Elisabetta, Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder, «NEURAL PLASTICITY», 2018, 2018, pp. 1 - 18 [articolo]
Fuchs, Claudia; Fustini, Norma; Trazzi, Stefania; Gennaccaro, Laura; Rimondini, Roberto; Ciani, Elisabetta*, Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice, «EUROPEAN JOURNAL OF NEUROSCIENCE», 2018, 47, pp. 1054 - 1066 [articolo]
