55393 - Organic Chemistry

Learning outcomes

At the end of the class the student has a basic knowledge of the different types of organic compounds and the mechanism of the most important reactions. Also, he has a good knowledge of the structure and reactivity of the main families of bio-molecules.

Course contents

Chemical bond and carbon hybridization states. Resonance. Physical properties of organic molecules. Basic notions of chemical reactivity. The idea of reaction mechanism. Alkanes and cycloalkanes. Halogenation of alkanes. Alkene and alkyne. Addition to the CC double bond. Alkene synthesis from alcohols. General notions of organic nomenclature. Conformational analysis. Cis-trans (E-Z) isomerism. Stereoisomerism in cyclic compounds. Chirality and chiral molecules: ena ntiomersand diastereomers. R/S isomerism. Conjugate unsaturated systems. Alcohols,ethers and phenols. Aldehydes and ketones: the reactivity of the carbonyl group, acidity of "alpha" bhydrogens, the aldol reaction, acetal formation, oxidation reactions. Carboxylic acids and acyl derivatives.The reactivity of the acyl compounds: the nucleophilic substitution at the carbonyl group. Benzene and benzene derivatives: structure of the benzene ring and nomeclature. Amines. Carbohydrates: monosaccharides (D‑glucose and D‑fructose), disaccharides (sucrose, maltose, cellobiose), polysaccharides. Cyclic structures of monosaccharides and disaccharides. Fisher and Haworth representations. Protein and aminoacids. The peptide bond. The Primary Structure of peptides. The Secondary, tertiary and quaternary structure of proteins. Lipids: fatty acids, fats and oils, phospholipids, steroids.

Readings/Bibliography

- Brown, Foote, Iverson, Anslyn "Chimica Organica" 4°Ed. EdiSES

- R.J.Fessenden, J.S.Fessenden "Chimica Organica", Ed. Piccin, Padova.

- T.W.Solomons "Fondamenti di Chimica Organica", Ed. Zanichelli, Bologna.

-J. McMurry "Chimica Organica", Ed. Piccin, Padova.

Teaching methods

Theoretical lectures. Problem solution.

Assessment methods

Oral examination

Teaching tools

Problem solution

Office hours

See the website of Andrea Bottoni