90932 - BIOMOLECULAR BASIS OF ANATOMICAL PATHOLOGY

Conoscenze e abilità da conseguire

Discuss the principal epidemiologic, morphologic, phenotypic, clinicopathologic features, and etiopathogenesis of common neoplastic and non neoplastic disorders, focusing on cardiovascular and neuromuscolar disorders. Describe the methods used to process and analyze tissue samples for diagnostic Anatomic Pathology, including histopathology and ultrastructural laboratory instrumentation and devices. Discuss innovative technologies for early diagnosis of disease, and for the identification of new molecular targets for tumor therapies.

Contenuti

 Definition of Anatomic Pathology

 Methods and Techniques in Anatomic Pathology

 Tumor classification

 Tumor of Central Nervous System and of pituitary: pathology and molecular diagnostics

 Neurodegenerative diseases: pathology and molecular diagnostics 

 Neuromuscular diseases: muscle pathology 

 Ultrastructural diagnostic (Electron microscopy) 

 Ultrastructural markers in Tumor diagnosis 

 Molecular diagnostic and prognostic markers in solid tumors 

 Tumors of the respiratory system: pathology and molecular diagnostics 

 Tumors of gastroenteropancreatic system: pathology nd molecular diagnostics 

 Tumors of the female reproductive system: pathology and molecular diagnostics 

 Tumors of the endocrine and neuro-endocrine system: pathology and molecular diagnostics 

The course will include 1 CFU of practical activity (Laboratory) through viewing and discussion of slides and interpretation of molecular data.

Testi/Bibliografia

Kumar, Cotran, Robbins "Basic Pathology", Saunders eds

World Health Classification of Central Nervous System Tumor 2021 5ed.

Metodi didattici

Conventional lectures and student working group

Case study

Hybrid and Integrative Digital Teaching

Modalità di verifica e valutazione dell'apprendimento

The student will be evaluated after oral examination about:

1. General principles of Anatomic Pathology and Molecular Diagnostics (Techniques and methodology)

2. Histopathological and molecular features of solid tumors

3. Discussion of case

 

Date of oral exam:

16.06.2025

07.07.2025

22.09.2025

Oral examination. Each student is examined by at least two different teachers. As a rule, no fewer than three questions are asked by two different teachers. To pass the exam, the student must provide adequate answers to all the questions. The final grade is based on the overall collegial assessment by the teachers of the student's ability to know, understand, and expose the specific subjects under examination in a concise and complete manner.

Final grades will be assigned according to the following criteria:

-Outstanding 30/30L: full preparation, consolidated and without inaccuracies on the topics covered in the integrated course. Ability to promptly frame the topic. Ability to analyze and connect independently different topics. Concepts in the right succession and full command of the specific language with some original elaboration by the student.

-Excellent 29-30/30: full preparation, consolidated and without significant inaccuracies on the topics covered in the course. Ability to promptly frame the topic. Ability to analyze and connect independently. Concepts in the right succession and full command of the specific language.

-Very good 27-28/30: preparation of very good level, but with significant inaccuracies compromising the achievement of full marks. Ability to analyze and link independently. Exposure of concepts in the right succession and with appropriate language.

-Good 23-26/30: preparation of good level, but with important inaccuracies in the presentation. Ability to analyze and link after input from the teacher. Exposure of concepts in the right succession and with appropriate language.

-Sufficient 18-22/30: knowledge limited to the basic concepts without serious gaps, only after input from the teacher. Exposition of concepts and language acceptable as a whole.

-Insufficient <18/30: lack of preparation. Serious and repeated conceptual errors.

 

Strumenti a supporto della didattica

Ex -cathedra teaching, conventional

Student working Group about main diagnostic issues

Case study and plenary discussion

Orario di ricevimento

Consulta il sito web di Sofia Asioli

Orario di ricevimento

Consulta il sito web di Sofia Asioli

Consulta il sito web di Antonio De Leo

Consulta il sito web di Antonio De Leo