84508 - ENDOCRINE PHARMACOLOGY

Conoscenze e abilità da conseguire

Describe the classification, mechanism of action, indications, and side effects of drugs for the treatment of endocrine and metabolic diseases.

Contenuti

Lecture 1 (2 h). ANTIDIABETIC DRUGS. Compare and contrast mechanisms of action, indications, contraindications, adverse drug reactions of insulin analogues, metformin, sulphonylureas, incretin-based drugs (GLP-1 receptor agonists and DPP4 inhibitors), SGLT2 inhibitors. Critical analysis of current guidelines.

Lecture 2 (2 h). DRUGS ACTING ON THYROID FUNCTION. Describe the mechanisms of action, indications, contraindications, adverse drug reactions of drugs used to treat hypothyroidism (L-thyroxine) and hyperthyroidism (carbimazole, propylthiouracil, Iodine-131). The role of beta-blockers. Drug effect on the thyroid.

Lecture 3 (2 h). DRUGS ACTING ON HORMONE RECEPTORS. Describe the mechanisms of action, indications contraindications, adverse drug reactions and prescribing criteria of contraceptives, including generations, formulations (oral, patch, intrauterine devises), pharmacodynamics (agonists, modulators), therapeutic uses. Drugs used for termination of pregnancy.

Lecture 4 (2 h). DRUGS ACTING ON BONE AND MINERAL HOMEOSTASIS. Describe the mechanisms of action, indications contraindications, adverse drug reactions and prescribing criteria of drugs used for osteoporosis (bisphosphonates, raloxifene, denosumab) Critical analysis of current guidelines. Drugs affecting bone metabolism (e.g., anticoagulants, glucocorticoids, anticancer drugs, antiepileptic drugs).

Testi/Bibliografia

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Metodi didattici

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Modalità di verifica e valutazione dell'apprendimento

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Strumenti a supporto della didattica

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Orario di ricevimento

Consulta il sito web di Emanuel Raschi