- Docente: Emanuel Raschi
- Crediti formativi: 1
- SSD: BIO/14
- Lingua di insegnamento: Inglese
- Modalità didattica: Convenzionale - Lezioni in presenza
- Campus: Bologna
- Corso: Laurea Magistrale a Ciclo Unico in Medicine and Surgery (cod. 9210)
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dal 07/03/2025 al 28/03/2025
Conoscenze e abilità da conseguire
Describe the mechanism of action, indications and limitations of oncologic and antiemetic drugs.
Contenuti
Lecture 1 (2 h). ANTICANCER DRUGS – Part A. Compare and contrast mechanisms of action, indications, contraindications, adverse drug reactions of chemotherapy (traditional chemotherapy; e.g., anthracyclines, taxanes)
Lecture 2 (2 h). ANTICANCER DRUGS – Part B. Compare and contrast mechanisms of action, indications, contraindications, adverse drug reactions of targeted therapy (monoclonal antibodies vs small-molecules), including immunotherapy (immune checkpoint inhibitors) and hormone therapy (tamoxifen).
Lecture 3 (2 h). ANTIEMETIC DRUGS. Describe the mechanisms of action, indications and limitations of antiemetic medications: anti-dopaminergic drugs (domperidone vs metoclopramide), 5-HT3 receptor antagonists (ondansetron), tachykinin NK1 receptor inhibitors (aprepitant). The role of corticosteroids. Combination regimens. Classify the emetogenic potential of anticancer drugs.
Lecture 4 (2 h). SAFE PRESCRIBING IN ONCOLOGY. Understand peculiarities of drug development approach for oncological drugs. Prediction and management of clinically-relevant interactions and adverse drug reactions, with a clinical case discussion.
Testi/Bibliografia
Suggested texbooks:
1) Hitchings, Lonsdale, Burrage, Baker. The top 100 drugs. Clinical pharmacology and practical prescribing. 2nd Edition, 2019, Elsevier.
2) Goodman and Gilman’s Manual of Pharmacology and Therapeutics. 2nd Edition. 2014. The McGraw-Hill Companies.
Metodi didattici
See english version
Modalità di verifica e valutazione dell'apprendimento
See english version
Strumenti a supporto della didattica
See english version
Orario di ricevimento
Consulta il sito web di Emanuel Raschi
SDGs


L'insegnamento contribuisce al perseguimento degli Obiettivi di Sviluppo Sostenibile dell'Agenda 2030 dell'ONU.