97027 - Extracellular Vesicles and Nanomedicine

Academic Year 2024/2025

  • Teaching Mode: Traditional lectures
  • Campus: Bologna
  • Corso: Second cycle degree programme (LM) in Medical Biotechnology (cod. 9081)

Learning outcomes

At the end of the course, students will be i) acquainted with the basic techniques of extracellular vesicles isolation, purification and characterization; ii) instructed about the recommended international guidelines for extracellular vesicles isolation, purification and characterization; iii) made able to understand the suitability of different methods of extracellular vesicle isolation and purification in different biological fluids and from different biologic sources; iv) be upgraded about methods to assess the genomic and protein profiling of extracellular vesicles. Students will also learn biologic assays regarding extracellular vesicle bio-activity and basic methods and instruments for in vitro and in vivo imaging studies on extracellular vesicles. Students will also learn how to study extracellular vesicles in the context of advanced medical and cellular therapies.

Course contents

1-extracellular vesicles: biology and function

2-extracellular vesicles: methods of detection

3-extracellular vesicles: methods of isolation

4-extracellular vesicles: as diagnostic tools

5-extracellular vesicles in the biology and clinics HSCT transplant

6-extracellular vesicles in the biology and clinics of CAR-T cells

 

Readings/Bibliography

slides ppt presentations

Teaching methods

frontal lecture

Assessment methods

viva voce

Teaching tools

ppt presentations

Office hours

See the website of Massimiliano Bonafè