B1774 - CHIMICA ANALITICA E INORGANICA

Learning outcomes

The course aims to lead students to understand and optimize common analytical procedures and the application of analytical determinations for the characterization of products/materials and processes in various industrial fields. Laboratory activities introduce the student to the main analytical techniques and their initial applications to materials.

Course contents

THEORY:

Fundamentals of Statistics in Analytical Chemistry: Quality of analytical data. Significant figures. Sources of uncertainty. Errors in chemical analysis; error propagation. Errors: gross, systematic, random. Accuracy and precision. Methods for reporting analytical data. Significance tests: Student's t test. Accuracy tests. Precision tests. Comparison of two samples.

Acids and bases in aqueous solvents: Strength of acids and bases. Polyfunctional acids and bases. Buffer solutions and ampholyte solutions. Systematic treatment of chemical equilibria. pH calculations. Acid-base titrations. Methods for evaluating the equivalent point of a titration. Titration error. Notes on acids and bases in non-aqueous solvents: Acid and alkaline properties of solvents. Solvent effects in acid-base reactions.

Inorganic chemistry and complexometry: Transition metals in the periodic table of elements and general properties of d-block elements. Introduction to d-block metal complexes: types of ligands, coordination number and structure, isomers and chirality, nomenclature. Structures and bonding of coordination compounds. Conditional and thermodynamic constants. Complexometric titrations of transition metal ions. EDTA and analytical applications. Interferents and masking.

Instrumental Analytical Chemistry: Main components of an analytical instrument. Statistics of instrumental analysis. Linear and straight line regression. Limit of detectability and sensitivity of instrumental chemical analysis. Signal-to-noise ratio. Standard addition. Confidence interval of a concentration obtained from a calibration line and by the addition method.

UV-Vis absorption spectrometry: Principles, instrumentation, operating conditions and quality control of spectrophotometric measurements. Construction of instrumental calibration line and Bouguer - Lambert - Beer law.

Atomic absorption spectrometry: Principles, instrumentation. Methods of qualitative and quantitative analysis of transition metal ions.



LABORATORY:

The topics of the theoretical part will be the subject of laboratory experiences whose objective will be to consolidate the student's preparation. In particular, the programme will focus on the following laboratory exercises for quantitative analyses:

1. Complexometric titration with EDTA

2. UV/VIS spectroscopy

3. Atomic spectroscopy

Readings/Bibliography

Recommended text books:

J.C. Miller and J.N. Miller, Statistics and Chemometrics for Analytical Chemistry, 6th ed., Prentice Hall (UK), 2010

D.C. Harris, “Chimica Analitica Quantitativa”, Zanichelli, Bologna,

D.A. Skoog, D.M. West, F.J. Holler, S.R. Crouch, “Fondamenti di Chimica Analitica”, EdiSES, Napoli

D.A. Skoog, D.M. West, F.J. Holler, S.R. Crouch, Chimica Analitica Strumentale, III Ed., Edises, 2009 (ISBN:9788879593427)

K. A. Rubinson, J. F. Rubinson, Chimica Analitica Strumentale, Zanichelli, 2002

Teaching methods

A series of lectures (individual learning) and laboratory experiences (group work) are planned.

All teaching materials will be made available on https://iol.unibo.it.

Attendance at the laboratory is compulsory. Attendance will be ascertained by signature. In order to fulfil the attendance obligation, it is necessary to attend at least 75% of the practical experiences planned for the laboratory part. In the event of unavailability, even if only partial, of a student for a laboratory experience, teachers must be contacted immediately to identify an alternative date or laboratory activity.

In view of the types of activities and teaching methods adopted, attendance of this training activity requires all students to complete modules 1 and 2 in e-learning mode [link] and to participate in module 3 of specific training on health and safety in the workplace. Information on the dates and procedures for attending module 3 can be found in the appropriate section of the course website

Assessment methods

The assessment of learning takes place through the evaluation of: laboratory activities and a final written examination.

The duration of the final written examination is 2 hours. The use of textbooks, the periodic table and lecture notes (or slides) is not permitted. It is compulsory to present oneself with a calculator (calculators available on devices such as tablets or mobile phones are not allowed) and the necessary diagramming equipment (pencils, ruler, square, eraser). The material on which to write the tests (protocol sheets, graph paper, etc.) will be made available by the teachers. The written examination consists of: a) multiple-choice and true/false questions; b) open question. The assessment of the written test is expressed in thirtieths and will be passed if the mark obtained is greater than or equal to 18/30.

The assessment of the laboratory activity is based on a group laboratory report and is expressed in thirtieths. The laboratory activity will be passed if the group laboratory report mark is greater than or equal to 18/30.

The weighted average of the overall laboratory grade (weight 40%) and the grade obtained in the written exam (weight 60%) determines the final grade.

Passed final marks can be refused up to two times.

Teaching tools

All teaching material is deposited on the UniBo 'Insegnamenti Online' platform (https://iol.unibo.it/). Handouts for laboratory experiences will be provided. Video projector and blackboard will be used during classroom lectures. Suggested tests will be provided.

Office hours

See the website of Andreas Stephan Lesch

See the website of Valentina Marassi