75265 - Pharmacology

Learning outcomes

The course provides knowledge of the basic principles of pharmacology, with special attention to drugs of CNS, inflammation, pain, musculo-skeletal system

Course contents

Pharmacokinetics:   absorption, distribution, metabolism and elimination of drugs

Main pharmacokinetic parameters: bioavailability, volume of distribution, AUC, Cmax, Tmax, clearance)

Pharmacodynamics:  mechanisms of drug action, agonists, antagonists, relation between drug concentration and effect

Drug-drug interactions

Notes on clinical developement of drug and pharmacovigilance.

Drugs acting on the central nervous system

Basics of hypnotics and sedatives, antipsychotics, antidepressants and antiepileptics

Opioid analgesics, Local anesthetics, Drugs for spasticity

Cardiovascular agents

Diuretics; Antihypertensive agents; Anticoagulant and antiplatelet drugs

Drug treatment of Asthma e COPD

Drug therapy of inflammation

Non steroidal antiiflammatory drugs (NSAIDs) and paracetamol; Antiinflammatory corticosteroids

General principles of pain therapy

Antimicrobial chemotherapy

General principles of antimicrobial chemotherapy; Antimicrobial agents: antibacterial and antifungal agents 

Illegal use of drugs in sports and exercise

Readings/Bibliography

Karen Whalen, Le basi della Farmacologia. Terza edizione italiana. 2020. Zanichelli Editore

Teaching methods

Lectures

Assessment methods

Questionnaire consisting of 31 questions with 4 possible answers of which only one is correct. The questions concern the whole program of the course.

Teaching tools

Teaching material (access restricted to UNIBO student) can be downloaded at https://virtuale.unibo.it

Office hours

See the website of Domenico Motola