- Docente: Andrea Buscaroli
- Credits: 3
- SSD: MED/14
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Ravenna
- Corso: Single cycle degree programme (LMCU) in Medicine and Surgery (cod. 5906)
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from Mar 03, 2025 to May 06, 2025
Learning outcomes
Knowledge and skills to be achieved
The course aims to provide the student with the essential elements for general theoretical and practical knowledge of the main primary and secondary diseases and syndromes involving, from a medical point of view, the kidneys and excretory tracts with the aim of providing synthetic elements for:
1. an appropriate knowledge and a correct methodological approach;
2. a characterization of the pathogenesis and the histological-morphological picture;
3. the acquisition of clinical pictures and knowledge of prevention, differential diagnostics, clinical course, decision making and possible complications.
At the end of the course the student knows the basic notions of the main pathologies of nephrological interest in their acute phase and the biochemical, instrumental and clinical investigations necessary for their diagnosis and outlines of therapy.
Course contents
Reminder of anatomy and physiology
Nephrological semiotics (clinical, laboratory tests, diagnostic imaging, renal biopsy)
Water balance and pathological conditions, acid-base balance and electrolyte disorders
Glomerular nephropathies: clinical presentation and pathogenetic mechanisms with in-depth analysis of nephritic and nephrotic syndrome. Minimal lesion GN, focal and segmental sclerosing GN, membranous GN, post-streptococcal/post-infectious GN, IgA nephropathy, membrano-proliferative GN and complement-related glomerulopathies, rapidly progressive GN and ANCA-related vasculitis
Secondary glomerular nephropathies: Lupus nephritis, Diabetic nephropathy, Glomerulopathies in the course of multiple myeloma and/or Amyloidosis, Glomerulopathies in the course of cryoglobulinemia
Pictures of thrombotic microangiopathy and hemolytic uremic syndrome
Acute kidney injury (AKI), pathophysiology and main clinical pictures: pre-renal, organic and post-renal forms
Hereditary nephropathies: Adult Polycystic Disease and other cystic nephropathies, Alport Syndrome, Fabry Disease
Interstitial nephropathies: acute and chronic pyelonephritis, analgesic and immuno-allergic nephropathies
Kidney modifications during pregnancy
Renovascular hypertension, renal infarction, atheroembolic nephropathy
Chronic kidney disease: epidemiology, and staging; progression of renal failure; main clinical alterations in the conservative phase and in the uremic phase including osteo-mineral disease.
Conservative therapy including the nutritional aspect
Dialysis replacement therapy (hemodialysis and peritoneal dialysis)
Kidney transplant
Readings/Bibliography
Harrison, Principles of internal medicine, 20th ed., Milan, CEA Casa Editrice Ambrosiana, 2021 (or 21st edition in English)
Garibotto-Pontremoli, Manual of Nephrology, and Minerva Medica
For consultation: Comprehensive Clinical Nephrology, R. J. Johnson; J. Feehally; J. Floege; M. Tonelli, Elsevier Ed.
Teaching methods
Lectures and interaction with students
Assessment methods
At least 3 in-presence exam sessions
Teaching tools
Updated teaching material provided during the course in PDF format available on "virtuale"
Office hours
See the website of Andrea Buscaroli