84443 - Cancerous and Precancerous Histopathology Laboratory

Learning outcomes

Identify the histopathology of cancerous and precancerous lesions through slide review.

Course contents

Drill lesson 1. Intestine

Intestinal adenomatous polyp; Intestinal adenocarcinoma; Highly infiltrating colon cancer; Poorly differentiated colon cancer; Mucinous rectal cancer; Hepatic metastasis of carcinoma.

Drill lesson 2. Female reproductive tract and bladder.

Leiomyoma (fibroid); Breast fibroadenoma; Breast adenocarcinoma; Papillary carcinoma of the bladder; Bladder cancer.

Drill lesson 3. Skin. 

Basocellular carcinoma; Squamous cell skin carcinoma; Lymphnode metastasis of squamous cell carcinoma; Leukoplakia of the gum; Verrucae (wart); Melanocytic nevus;

Drill lesson 4. Musculoskeletal and lymphatic. 

Fibrosarcoma; Chondrosarcoma; Polymorphic sarcoma; Ewing sarcoma; Hodgkin lymphoma; Plasmacytoma; Lymphnode metastasis of carcinoma.

Drill lesson 5. Lung and kidney.

Bronchial adenocarcinoma; Small cells lung cancer (microcytoma); Liver metastasis of small cell lung cancer; Kidney metastasis of small cell lung cancer; Lung metastasis of carcinoma; Kidney cancer.

 

 

Readings/Bibliography

For each histological preparation, the following supports are available:

A "virtual slide", which consists of a scan of the preparation that can be "browsed" online at: https://unibo.smartzoom.com. Access by UNIBO credentials, then click on Cancerous and precancerous histopathology lab. A description of each sample is also available by clicking on "Information".

A video explaining the most relevant aspects of the preparations is available on the "virtuale" site under "Videos".

Teaching methods

The course is divided into 3 classes (2h each) and 5 drill lessons (2h 30 min each). During the 3 classes, all the tissues samples will be described using the virtual microscopy smartzoom platform. The drill lessons will be done in 2 turns of 75 min each. Turn participation will be self organized by students.

Attendance to learning activities is mandatory; the minimum attendance requirement to be admitted to the final exam is 60% of lessons. For Integrated Courses (IC), the 60% attendance requirement refers to the total amount of I.C. lessons. Students who fail to meet the minimum attendance requirement will not be admitted to the final exam of the course, and will have to attend relevant classes again during the next academic year.

Professors may authorise excused absences upon receipt of proper justifying documentation, in case of illness or serious reasons. Excused absences do not count against a student’s attendance record to determine their minimum attendance requirement.

Assessment methods

During the exam, which is part of the IC. "Neoplasia as Disease Model", the student will be asked to recognize and discuss one or more preparations randomly chosen among those shown during the course. The student will be requested to explain through which logical procedure he/she has reached the conclusions. The grade obtained (necessarily greater than or equal to 18) will be mediated in weighted form with the votes obtained in the other modules of the IC, contributing to determining the final grade as follows.

Oral exams
Cancerous and precancerous histopathology laboratory
Cancer Biology: 1 oral question
Oncological Pharmacology; 1 oral question
Written exams (Multiple choice, 4 answers, 1 point for each correct answer, no penalty for wrong answers)
Medical oncology: 15 questions
General Surgery: 5 questions
Oncological Radiology: 5 questions
Clinical Psychology: 5 questions

Marks
Histopathology: max 30 points, weight 1/11
Cancer Biology, max 30 points, weight 3/11
Oncological Pharmacology, max 30 points, weight 1/11
Written part: 1 point for each question, max 30 points total, weight: 6/11
Final mark: (Written*6/11) + Histopathology/11 + (Biology*3/11) + Pharmacology/11
Full marks in all parts => 30 cum laude

To pass the exam the student must obtain a pass mark in each discipline, i.e.
Histopathology: at least 18/30
Biology: at least 18/30
Pharmacology: at least 18/30
Medical Oncology: at least 8/15 correct answers
Surgery: at least 3/5 correct answers
Radiology: at least 3/5 correct answers
Psychology: at least 3/5 correct answers

Teaching tools

The virtual microscopy zoom platform mentioned above.

Office hours

See the website of Fabio Dall'Olio