- Docente: Giuseppe Gargiulo
- Credits: 8
- SSD: BIO/18
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: First cycle degree programme (L) in Biological Sciences (cod. 8012)
Learning outcomes
Main purpose of this course is to provide some basic knowledges of genetic methods and to explain necessary elements for understanding advanced genetic problems.
Course contents
DNA: the genetic material, the structure of DNA, DNA
replication, mitosis and meiosis. Mendelian genetics, monohybrid
crosses, crosses involving multiple loci, chi-squared test.
Chromosomal basis of inheritance, sex determination and sex-linked
characteristics, gene dosage compensation. Extensions of mendelian
genetic analysis, multiple alleles, gene interaction, interaction
of sex and heredity, interaction of genes and environment. Maternal
effect. Pedigrees. Linked genes and recombination. Bacterial and
viral genetics. Non-mendelian inheritance, mitochondria and
chloroplasts. The genetic code. Gene mutations. Chromosomal
mutations. Transposable elements. Recombinant DNA technology:
DNA coning, restriction enzymes, agarose gel elecrophoresis,
Southern blotting, restriction maps, construction of genomic
libraries.
Readings/Bibliography
Pierce B. A. “GENETICA” - Edit. Zanichelli
Russell P. J. “GENETICA Un approccio molecolare” - Edit. Pearson
Hartl D.L. e Jones E.W. “ GENETICA Analisi di geni e genomi” Edit. EdiSES
Klug W. S. et al. CONCETTI DI GENETICA - Edit. Pearson
Griffiths A.J.F. et al. GENETICA 6^ edz. – Edit. Zanichelli
Teaching methods
Lectures. Practical work in the lab (one credit).
Assessment methods
Written and oral examinations. The student must solve genetic problems (written test) and answer to questions regarding topics of the program (oral examination).
Teaching tools
power-point
Office hours
See the website of Giuseppe Gargiulo