- Docente: Diego Savoia
- Credits: 6
- SSD: CHIM/06
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: Second cycle degree programme (LM) in Chemistry (cod. 8029)
Learning outcomes
The student will be able to choose the most aprropriate methodology to synthesize a target molecule, especially exploiting organometallic reagents, transition metal species or complexes, Lewis acids or radical processes with high selectivity, in terms of chemoselectivity, typeselectivity, constitutional selectivity and stereoselectivity.
Course contents
Definition of diverse selectivities: chemoselectivity, typeselectivity, constitutional selectivity (siteselectivity or locoselectivity, regioselectivity), stereoselectivity. Synthesis of enantiomerically pure compounds. Selectivity in organic reactions: substitution, elimination, addition to alkenes and alkynes, transition metal-mediated and catalyzed reactions, reactions of ate-complexes, addition to carbonyl compounds, aldol condensation, ring-openic reactions of tree-memberet cyclic compounds, functionalization of carbon-hydron bonds.
Readings/Bibliography
the teacher will give to all the students a lecture note covering all the programme.
Teaching methods
Learning will be facilitated by the presentation of selected reported examples of synthesis featuring high level of the diverse type of selectivity.
Assessment methods
At the end of the course there will be an oral examination. The student will present the content of a recent scientific report taken from an international journal of organic chemistry and dealing with one of the topics of the course
Teaching tools
The teacher will give all the students a lecture note covering the whole program and will largely make use of slides to present the reaction schemes and mechanisms.
Office hours
See the website of Diego Savoia